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Radda
10 days ago
5

Does increasing the size of an axial substituent always result in higher relative strain energies for the axial conformation

Biology
2 answers:
Tresset [1.6K]10 days ago
5 0
The increase in the size of an axial substituent does not always correlate with an increase in strain energy for the axial form. In some situations, a larger substituent can result in a longer bond between the carbon and the substituent, which does not escalate the relative strain energy for the axial configuration. An instance of this is seen in iodocyclohexane.
lana [1.7K]10 days ago
4 0
There is no inherent need to augment the size of the axial substituent, as strain energy in that configuration already rises. In some instances, while the size of the substituent may grow and thus the bond length between the carbon atom and the substituent increases, the deformation energy for the axial form does not show an increase.
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