Cells of the pancreas will incorporate radioactively labeled amino acids in to proteins. This "tagging" of newly synthesized pro

Question

2 months ago

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Cells of the pancreas will incorporate radioactively labeled amino acids in to proteins. This "tagging" of newly synthesized pro

teins enables a researcher to track their location. In this case, we are tracking an enzyme secreted by pancreatic cells. What is its most likely pathway

Biology

2 answers:

s2008m [2.3K] · Answer 1 · 2026-02-23T15:01:18+03:00

Answer:

The pathway likely taken is ER - Golgi - vesicles that merge with the plasma membrane.

Explanation:

The endomembrane system comprises a complex network of internal membranes. It was first identified in the late 19th century when Camillo Golgi observed that a specific stain selectively colored certain cellular membranes. Golgi believed these membranes were interconnected; however, subsequent developments in microscopy and biochemical analysis revealed that the organelles within the endomembrane system function as distinct compartments with specialized roles.

11111nata11111 [2.5K] · Answer 2 · 2026-02-23T14:58:05+03:00

Answer: the full question is as follows.

Cells in the pancreas incorporate radioactively labeled amino acids into proteins, enabling researchers to track these proteins’ locations within a cell. In this case, we are observing an enzyme eventually secreted by the pancreatic cell. What is the most likely pathway for these proteins in the cell?

A. ER - Golgi to nucleus

B. Golgi - ER - lysosomes

C. Nucleus - ER - Golgi

D. ER - Golgi - vesicles that unite with the plasma membrane

E. ER - lysosomes - vesicles that combine with the plasma membrane

Explanation: The correct choice is option D

ER - Golgi - vesicles that merge with the plasma membrane.

Acinar cells within the endocrine pancreas (which secrete substances into the bloodstream) possess a highly developed endoplasmic reticulum (ER) system, facilitating the modification and transport of newly created proteins in the secretory pathway. Along with executing protein synthesis and processing, each protein produced in the ER must undergo specific secondary modifications and folding necessary for adequate transport to destination organelles, such as the Golgi apparatus, zymogen granules (which store digestive enzymes), and lysosomes, or to membrane sites (vesicles that fuse with plasma membranes).

Environmental factors, including alcohol, smoking, altered metabolism, and foreign substances, can negatively impact protein processing in the ER.