Explanation of two families with comparable wealth and influence in Verona: they are engaged in a long-standing feud that escalated through fatalities. The bloodshed of the innocent leads to unclean hands for the innocent, and from the deaths of these rivals, two lovers take their own lives, which prompts their families to finally reconcile.
The answer (APEX) is: "This difference between us still persists to this day."
Between chapters 21 and 22, there is a notable change as the tone shifts to a more cynical perspective, marking a significant structural transition. Thus, the answer to what occurs between these chapters is the enduring change in tone towards cynicism.