The melting point for DNA having 50% GC content is 104 °C
Additional explanation
DNA forms a base pair of bonds comprising adenine pairing with thymine and guanine with cytosine. These links are hydrogen bonds.
The presence of three hydrogen bonds between guanine-cytosine and two between adenine-thymine means that heating DNA for denaturation requires a higher energy input.
The proportion of guanine and cytosine in DNA (the GC content) is directly related to the melting point, which is the temperature at which DNA separates.
When we graph the melting point of DNA (y-axis) against the percentage of GC content (x-axis), it produces a linear equation.
Using the line equation (y = 0.5x + 79) with a GC content of 50%, substituting value x gives us the melting point y for DNA:
y = 0.5(50) + 79
Resulting in y = 104 °C
Further reading
the components of the DNA molecule
the structure resembling rungs in the DNA ladder
the components of a nucleotide for DNA and RNA.
the antiparallel structure of DNA strands
Keywords: GC content, DNA structure, melting point, hydrogen bonds, adenine, thymine, guanine, cytosine, denaturation