Question from alternative source
Numerous mutation types can arise in the body. Cystic fibrosis is a genetic condition attributed to various mutations in the CFTR gene. A specific mutation in the CFTR gene related to cystic fibrosis results in an earlier-than-expected termination of translation in the gene sequence. Which kind of mutation leads to this translation error resulting in cystic fibrosis?
- silent
- missense
- nonsense
- deletion
Answer:
Nonsense
Explanation:
Nonsense mutations refer to those that create a premature stop codon. The stop codons include UAG, UAA, and UGA. This situation could occur if a nucleotide substitution happens in the mRNA codon UAC (which codes for the amino acid Tyrosine) changing to UAG (which signifies a stop codon).
Upon reaching this codon, the translation machinery would interpret it as a directive to end translation. Consequently, the mRNA would be released, leading to a truncated version of the amino acid, which is likely not functional and could be flagged for destruction by the cell.
C. What is the connection between acids and bases and the cleaning products sector?
multiple pathwaysligands/signaling moleculesinorganic phosphateinactive relay proteins
The answer is a
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