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AleksAgata
1 day ago
6

In which order do the necessary enzymes act to repair a thymine dimer by nucleotide excision repair?a) nuclease, dna polymerase,

rna primaseb) helicase, dna polymerase, dna ligasec) dna ligase, nuclease, helicased) dna polymerase, rna polymerase, dna ligasee) nuclease, dna polymerase, dna liga?
Biology
2 answers:
garik1379 [619]1 day ago
7 0

Answer:

The right choice is b) "helicase, dna polymerase, dna ligase".

Explanation:

The occurrence of thymine dimers is the most prevalent form of DNA damage resulting from UV radiation. Cells possess a repair mechanism known as nucleotide excision repair to rectify this damage. In this process, a helicase unwinds the double-stranded DNA, creating a bubble at the damage site. Once the damaged part is excised, DNA polymerase fills in the gap where DNA is missing, and DNA ligase reconciles the previously separated double-stranded DNA segments.

garik1379 [619]1 day ago
3 0
To fix a thymine dimer via nucleotide excision repair, the sequence of enzyme activity is Endonuclease, DNA polymerase I, and DNA ligase. Two primary methods exist for repairing thymine dimers; one is photoreactivation, where an enzyme activated by blue light repairs the dimer, thus restoring the proper base pairing. The alternative method is excision repair, involving the uvr system that removes the dimer, with the gap filled by DNA polymerase I's proofreading capability.
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