During translation, the new polypeptides are often directed to specific parts of the cell by the presence or absence of short se

Question

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During translation, the new polypeptides are often directed to specific parts of the cell by the presence or absence of short se

quences of amino acids called signal sequences. Which peptides would you expect to find in the polypeptide that will eventually fold to become an ion channel protein?
Select all that apply.
a. an internal signal peptide
b. an amino-terminal signal
c. peptide a signal-anchor
d. peptide no signal peptide

Chemistry

1 answer:

Anarel [2.9K] · Answer 1 · 2026-03-04T13:45:33+03:00

Answer:

The correct choice is b. an amino-terminal signal

Explanation:

A polypeptide that will ultimately organize into an ion channel protein, which is a type of integral membrane protein, possesses an amino-terminal signal that guides it to the endoplasmic reticulum (ER) and subsequently to the membrane. This signal generally consists of a core sequence of 6 to 12 amino acids along with one or more basic amino acids. Once inside the ER, this signal is cleaved off.