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kvv77
2 months ago
6

many different types of mutations can occur within the body .cystic fibrosis is a genetic disorder that is caused by different m

utations within the cftr gene
Biology
1 answer:
vlada-n [2.5K]2 months ago
8 0

Question from alternative source

Numerous mutation types can arise in the body. Cystic fibrosis is a genetic condition attributed to various mutations in the CFTR gene. A specific mutation in the CFTR gene related to cystic fibrosis results in an earlier-than-expected termination of translation in the gene sequence. Which kind of mutation leads to this translation error resulting in cystic fibrosis?

  • silent
  • missense
  • nonsense
  • deletion

Answer:

Nonsense

Explanation:

Nonsense mutations refer to those that create a premature stop codon. The stop codons include UAG, UAA, and UGA. This situation could occur if a nucleotide substitution happens in the mRNA codon UAC (which codes for the amino acid Tyrosine) changing to UAG (which signifies a stop codon).

Upon reaching this codon, the translation machinery would interpret it as a directive to end translation. Consequently, the mRNA would be released, leading to a truncated version of the amino acid, which is likely not functional and could be flagged for destruction by the cell.

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