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IceJOKER
2 months ago
15

Place these steps of the insulin signaling pathway in the correct order from insultin is secreted to glucose enters the cell. Pl

ace all eight steps. The abbreviation PIP2 is used for phosphatidylinositol 4,5-bisphosphate; PIP3 is used for phosphatidylinositol 3,4,5-trisphosphate.1. Activation of Akt2. Binding of insulin to the alpha subunit of the insulin receptor3. Phosphorylation of IRS proteins4. Conversion of PIP2 to PIP35. Glut4 receptors transported to cell membrane6. Phosphorylation of phosphinositide 3-kinase (PI-3K)7. Activation of PIP3-dependent protein kinase B (PDK1)8. Activation of insulin receptor tyrosine kinase
Biology
1 answer:
lana [2.4K]2 months ago
8 0

Answer:

1. Insulin binds to the alpha subunit of the insulin receptor

2. Insulin receptor tyrosine kinase is activated

3. IRS proteins are phosphorylated

4. PDK1, a PIP3-dependent protein kinase, is activated

5. Phosphinositide 3-kinase (PI-3K) is phosphorylated

6. PIP2 is converted to PIP3

7. Akt is activated

8. Glut4 receptors are moved to the cell membrane

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