As per ICH E6 4.8.9, if a participant cannot read the informed consent, an unbiased witness must be present for the entire discussion. The informed consent is provided to the participant and read aloud to ensure comprehension. Once the participant signs, the witness also needs to sign and date the document. This signature indicates that the witness confirms the information was adequately explained and the participant has provided consent.
Answer: Soraya couldn't detect the mold until the fifth day because the bacterial growth was still developing. Had she consumed the soup on day four, she might have fallen ill due to the presence of bacteria in it.
