• Neurotransmitters produce effects that occur rapidly.
• Hormones typically have effects that endure over a longer period.
Additional Details:
Neurotransmitters cross the synaptic cleft and bind to receptor proteins on the postsynaptic membrane to generate graded potentials. There are two categories:
• Inhibitory neurotransmitters
• Excitatory neurotransmitters
Excitatory neurotransmitters induce depolarization; for instance, acetylcholine attaches to receptor proteins causing ligand-gated ion channels to open. Inhibitory neurotransmitters lead to inhibitory postsynaptic potentials (IPSP), promoting hyperpolarization. Both hormones and neurotransmitters open ligand-gated channels, altering membrane permeability reflected as depolarization or hyperpolarization. External neurotransmitters usually produce a rapid bodily response to stimuli.
Hormones serve as chemical messengers traveling through the bloodstream to target organs or tissues, facilitating growth, development, metabolism, and reproduction, and exerting long-lasting effects.