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alexgriva
3 months ago
6

Barbiturates, including "truth serums" seen in movies like Meet the Fockers and sedatives that may have led to the untimely deat

h of Jimi Hendrix, are often synthesized using what type of reaction sequence involving two consecutive enolate alkylations

Chemistry
1 answer:
Alekssandra [3K]3 months ago
8 0

Answer:

Explanation:

Diethyl malonate possesses greater acidity compared to monocarbonyl substances (pKa=13) because its alpha hydrogens are linked to two carbonyl groups. Consequently, the malonic ester can be readily changed into its enolate ion by reacting it with sodium ethoxide in ethanol. When the malonic ester undergoes alkylation, a hydrogen atom in the alpha position becomes acidic, permitting another round of alkylation to yield a dialkylated malonic ester.

In this scenario, when diethyl malonate interacts with urea in the presence of sodium ethoxide base, the second alkylation step occurs within the molecule, producing a cyclic compound known as barbituric acid.

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Let's assume that the compound formula is as follows: Experiment 1: 1.00 g of the compound yields 1.95 g of AgCl. The molar mass of AgCl is 143.32 g/mol. Thus, the moles of AgCl for 1.95g are: The moles of Cl also equal 0.0136, considering that 1 mole of AgCl corresponds to 1 mole of Cl. Experiment 2: 1.00 g of the compound results in 0.900 g of CO2 and 0.735 g of H2O. The molar mass of CO2 is 44 g/mol, and for H2O, it's 18 g/mol. Therefore, the moles of C come to 0.0205 and the moles of H stand at 0.0816 (which is 2 times the moles of H2O). Now, from the provided details, it's derived that in 1.00 g of the compound, there are 0.0136 moles of Cl, 0.0205 moles of C, and 0.0816 moles of H. In terms of mass: Mass of Cl = 0.0136 * 35.5 = 0.4828 g. Mass of C = 0.0205 * 12 = 0.246 g. Mass of H = 0.0816 * 1 = 0.0816 g. Total mass = 0.4828 + 0.246 + 0.0816 + mass of N. Given that 1.00 = 0.8104 + Mass of N, it follows that Mass of N = 0.1896. Thus, upon dividing all moles by the smallest value, we find Cl = 0.0136 / 0.0135 = 1.0007; C = 0.0205 / 0.0135 = 1.52; H = 0.0816 / 0.0135 = 6.04; N = 0.0135 / 0.0135 = 1. Multiplying by 2 allows us to reach integer values: Cl = 2, C = 3, H = 12, N = 2.
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1.2×10²³ atoms.

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